Depew is located in Erie County, NY. The population is 15,324, making Depew the 4th largest city in Erie County.
There are 4 public schools in Depew with an average Homefacts rating of B. The total crime rate for Depew is very low , and there are 14 registered sex offenders residing in the city. Unemployment in Depew is moderate and the median home sales price is $0. Detailed and up-to-date Depew property reports are available for any property address.
Cities near Depew include Cheektowaga, Lancaster and Williamsville.