Santee is located in Orangeburg County, SC. The population is 946, making Santee the 7th largest city in Orangeburg County.
There are 1 public schools in Santee with an average Homefacts rating of D-. The total crime rate for Santee is moderate , and there are 17 registered sex offenders residing in the city. Unemployment in Santee is very high and the median home sales price is $0. Detailed and up-to-date Santee property reports are available for any property address.