16346 is zip code located in Seneca, Pennsylvania. The population is 3,316, making 16346 the largest zipcode in Seneca and the 3rd largest in Venango County.
There are 2 public schools in 16346 with an average Homefacts rating of B-. , and there are 3 registered sex offenders residing in the zip code 16346. Unemployment in 16346 is very high.