78578 is zip code located in Port Isabel, Texas. The population is 11,245, making 78578 the largest zipcode in Port Isabel and the 9th largest in Cameron County.
There are 5 public schools in 78578 with an average Homefacts rating of C. The total crime rate for Port Isabel is high , and there are 22 registered sex offenders residing in the zip code 78578. Unemployment in 78578 is high.