De Soto is located in Crawford County, WI. The population is 306, making De Soto the 5th largest city in Crawford County.
There are 4 public schools in De Soto with an average Homefacts rating of B-. The total crime rate for De Soto is very low, and there are 4 registered sex offenders residing in the city. Unemployment in De Soto is moderate and the median home sales price is $0.