Defiance is located in St. Charles County, MO. The population is 143.
There are 0 public schools in Defiance with an average Homefacts rating of NA. The total crime rate for Defiance is low , and there are 14 registered sex offenders residing in the city. Unemployment in Defiance is low and the median home sales price is $0. Detailed and up-to-date Defiance property reports are available for any property address.