Charleston is located in Mississippi County, MO. The population is 5,847, making Charleston the largest city in Mississippi County.
There are 4 public schools in Charleston with an average Homefacts rating of C-. The total crime rate for Charleston is low, and there are 16 registered sex offenders residing in the city. Unemployment in Charleston is moderate and the median home sales price is $0. Detailed and up-to-date Charleston property reports are available for any property address.