Charleston is located in Mississippi County, MO. The population is 5,847, making Charleston the largest city in Mississippi County.
There are 4 public schools in Charleston with an average Homefacts rating of C-. The total crime rate for Charleston is very low , and there are 15 registered sex offenders residing in the city. Unemployment in Charleston is moderate and the median home sales price is $0. Detailed and up-to-date Charleston property reports are available for any property address.