De Kalb is located in Buchanan County, MO. The population is 226, making De Kalb the 6th largest city in Buchanan County.
There are 1 public schools in De Kalb with an average Homefacts rating of B. The total crime rate for De Kalb is moderate , and there are 2 registered sex offenders residing in the city. Unemployment in De Kalb is low and the median home sales price is $0. Detailed and up-to-date De Kalb property reports are available for any property address.