85621 is zip code located in Nogales, Arizona. The population is 23,074, making 85621 the largest zipcode in Nogales and the largest in Santa Cruz County.
There are 20 public schools in 85621 with an average Homefacts rating of B-. The total crime rate for Nogales is low , and there are 11 registered sex offenders residing in the zip code 85621. Unemployment in 85621 is high.