De Soto is located in Jackson County, IL. The population is 1,478, making De Soto the 2nd largest city in Jackson County.
There are 1 public schools in De Soto with an average Homefacts rating of C-. The total crime rate for De Soto is low , and there are 1 registered sex offenders residing in the city. Unemployment in De Soto is very high and the median home sales price is $0. Detailed and up-to-date De Soto property reports are available for any property address.
Cities near De Soto include De Soto Township, Somerset Township and Hurst.